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Journal of Biomedical Optics

Spectroscopic methods for the photodiagnosis of nonmelanoma skin cancer
Author(s): Eleni Drakaki; Theognosia Vergou; Clio Dessinioti; Alexander J. Stratigos; Carmen Salavastru; Christina Antoniou
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Paper Abstract

The importance of dermatological noninvasive imaging techniques has increased over the last decades, aiming at diagnosing nonmelanoma skin cancer (NMSC). Technological progress has led to the development of various analytical tools, enabling the in vivo/in vitro examination of lesional human skin with the aim to increase diagnostic accuracy and decrease morbidity and mortality. The structure of the skin layers, their chemical composition, and the distribution of their compounds permits the noninvasive photodiagnosis of skin diseases, such as skin cancers, especially for early stages of malignant tumors. An important role in the dermatological diagnosis and disease monitoring has been shown for promising spectroscopic and imaging techniques, such as fluorescence, diffuse reflectance, Raman and near-infrared spectroscopy, optical coherence tomography, and confocal laser-scanning microscopy. We review the use of these spectroscopic techniques as noninvasive tools for the photodiagnosis of NMSC.

Paper Details

Date Published: 17 December 2012
PDF: 11 pages
J. Biomed. Opt. 18(6) 061221 doi: 10.1117/1.JBO.18.6.061221
Published in: Journal of Biomedical Optics Volume 18, Issue 6
Show Author Affiliations
Eleni Drakaki, Univ. of Athens (Greece)
Theognosia Vergou, Univ. of Athens (Greece)
Clio Dessinioti, Univ. of Athens (Greece)
Alexander J. Stratigos, Univ. of Athens (Greece)
Carmen Salavastru, Carol Davila Univ. of Medicine and Pharamacy (Romania)
Christina Antoniou, Univ. of Athens (Greece)


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