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Journal of Biomedical Optics • Open Access

Recovering intrinsic fluorescence by Monte Carlo modeling
Author(s): Manfred Muller; Benno H. W. Hendriks

Paper Abstract

We present a novel way to recover intrinsic fluorescence in turbid media based on Monte Carlo generated look-up tables and making use of a diffuse reflectance measurement taken at the same location. The method has been validated on various phantoms with known intrinsic fluorescence and is benchmarked against photon-migration methods. This new method combines more flexibility in the probe design with fast reconstruction and showed similar reconstruction accuracy as found in other reconstruction methods.

Paper Details

Date Published: 11 February 2013
PDF: 14 pages
J. Biomed. Opt. 18(2) 027009 doi: 10.1117/1.JBO.18.2.027009
Published in: Journal of Biomedical Optics Volume 18, Issue 2
Show Author Affiliations
Manfred Muller, Philips Research Nederland B.V. (Netherlands)
Benno H. W. Hendriks, Philips Research Nederland B.V. (Netherlands)

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