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Journal of Biomedical Optics

Semiautomatic and rapid quantification of heartbeat parameters in Drosophila using optical coherence tomography imaging
Author(s): Shou-Yuan Guo; Fang-Tsu Liao; Ming-Tsan Su; Cheng-Yi Chang; Hong-Ren Su; Jyun-Cin Huang; Wen-Chuan Kuo
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Paper Abstract

We report a semiautomatic algorithm that is specialized for rapid analysis of beat-to-beat contraction-relaxation parameters of the heart in Drosophila. The presented algorithm adapts the general graph theoretical image segmentation algorithm and a histogram-based thresholding algorithm, which can measure many cardiac parameters, including heart rate, heart period, diastolic and systolic intervals, and end-diastolic and end-systolic areas. Additionally, dynamic cardiac functions, such as arrhythmia index and percent fractional shortening, can be automatically calculated for all the recorded heartbeats over significant periods of time.

Paper Details

Date Published: 1 February 2013
PDF: 9 pages
J. Biomed. Opt. 18(2) 026004 doi: 10.1117/1.JBO.18.2.026004
Published in: Journal of Biomedical Optics Volume 18, Issue 2
Show Author Affiliations
Shou-Yuan Guo, National Taiwan Normal Univ. (Taiwan)
Fang-Tsu Liao, National Taiwan Normal Univ. (Taiwan)
Ming-Tsan Su, National Taiwan Normal Univ. (Taiwan)
Cheng-Yi Chang, National Taiwan Normal Univ. (Taiwan)
Hong-Ren Su, National Tsing Hua Univ. (Taiwan)
Jyun-Cin Huang, National Taiwan Normal Univ. (Taiwan)
Wen-Chuan Kuo, National Yang-Ming Univ. (Taiwan)

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