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Journal of Biomedical Optics • Open Access

In vivo label-free microangiography by laser speckle imaging with intensity fluctuation modulation
Author(s): Mingyi Wang; Yaguang Zeng; Xianjun Liang; Guanping Feng; Xuanlong Lu; Junbo Chen; Dingan Han; Guojian Yang

Paper Abstract

We present the theory of laser speckle imaging improved with intensity fluctuation modulation, where the dynamic speckle pattern can be isolated from its stationary counterpart. A series of in vivo experiments demonstrate the effectiveness of our method in achieving microangiography and monitoring vascular self-recovering process. All results show the convincing performance of our imaging method in both structural and functional imaging of blood flow, which may have potential applications in biological research and disease diagnosis.

Paper Details

Date Published: 2 December 2013
PDF: 6 pages
J. Biomed. Opt. 18(12) 126001 doi: 10.1117/1.JBO.18.12.126001
Published in: Journal of Biomedical Optics Volume 18, Issue 12
Show Author Affiliations
Mingyi Wang, Beijing Normal Univ. (China)
Yaguang Zeng, Beijing Normal Univ. (China)
Xianjun Liang, Foshan Hospital of Traditional Chinese Medicine (China)
Guanping Feng, Foshan Univ. (China)
Xuanlong Lu, Foshan Univ. (China)
Junbo Chen, Foshan Univ. (China)
Dingan Han, Foshan Univ. (China)
Guojian Yang, Beijing Normal Univ. (China)

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