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Journal of Biomedical Optics

Study of dynamic pressure-induced refractive index change using derivative total reflection method
Author(s): Jin Wang; Qing Ye; Zhichao Deng; Teng-Qian Sun; Wen-Yuan Zhou; Jian-Chun Mei; Chun-Ping Zhang; Jianguo Tian
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Paper Abstract

We report the dynamic refractive index (RI) change of tissue under a stepped compression load using a custom-built pressure apparatus. Angle-dependent reflectance profiles of biotissue samples are recorded, and the RI values are resolved using the derivative total reflection method. These results are relevant for understanding the mechanism of mechanical optical clearing, for investigating tissue dynamics under mechanical stimuli, and for other biomedical applications.

Paper Details

Date Published: 8 November 2013
PDF: 5 pages
J. Biomed. Opt. 18(11) 117005 doi: 10.1117/1.JBO.18.11.117005
Published in: Journal of Biomedical Optics Volume 18, Issue 11
Show Author Affiliations
Jin Wang, Nankai Univ. (China)
Qing Ye, Nankai Univ. (China)
Zhichao Deng, Nankai Univ. (China)
Teng-Qian Sun, Nankai Univ. (China)
Wen-Yuan Zhou, Nankai Univ. (China)
Jian-Chun Mei, Nankai Univ. (China)
Chun-Ping Zhang, Nankai Univ. (China)
Jianguo Tian, Nankai Univ. (China)

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