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Journal of Biomedical Optics

Role of contrast and fractality of laser speckle image in assessing flow velocity and scatterer concentration in phantom body fluids
Author(s): Cerine Lal; Arnab Banerjee; Narayanan Unni Sujatha
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Paper Abstract

Blood flow velocity and red blood cell concentration are of vital importance in assessing tissue microcirculation. Laser speckle contrast analysis is being considered as a promising tool in the qualitative assessment of flow velocity as well as scatterer concentration in different body fluids, though the quantification part still remains challenging. The fractal-based spatial correlation analysis of speckle flow images along with the corresponding contrast analysis for the quantitative assessment of flow and scatterer concentration is investigated. In this study, phantom body fluid solution (intralipid 20%) of different concentrations is pumped at different flow rates through the designed flow channel using a syringe pump and the corresponding speckle images are acquired. The fractality of the acquired speckle images in response to the changes in concentration of the fluid as well as the variations in fluid flow is analyzed along with the corresponding contrast-based analysis. Following this qualitative analysis, an experimental model is attempted toward quantification of these parameters from a single acquired speckle image by considering the contrast and fractality changes together.

Paper Details

Date Published: 18 November 2013
PDF: 8 pages
J. Biomed. Opt. 18(11) 111419 doi: 10.1117/1.JBO.18.11.111419
Published in: Journal of Biomedical Optics Volume 18, Issue 11
Show Author Affiliations
Cerine Lal, Indian Institute of Technology Madras (India)
Arnab Banerjee, Indian Institute of Technology Madras (India)
Narayanan Unni Sujatha, Indian Institute of Technology Madras (India)


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