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Journal of Biomedical Optics

Photoinduced cell morphology alterations quantified within adipose tissues by spectral optical coherence tomography
Author(s): Irina Yu. Yanina; Natalia A. Trunina; Valery V. Tuchin
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Paper Abstract

Morphological changes of the adipose tissue at phototreatment are studied in vitro using optical coherence tomography. The 200 to 600 μm fat tissue slices are used in the experiments. The observed change in the tissue structure was associated with fat cell lipolysis and destruction caused by the photodynamic effect. It is found that overall heating of a sample from room to physiological temperature leads to deeper and faster morphology tissue changes if other processing conditions are kept constant. These data support the hypothesis that photodynamic/photothermal treatment induces fat cell lipolysis during some period after treatment.

Paper Details

Date Published: 2 August 2013
PDF: 10 pages
J. Biomed. Opt. 18(11) 111407 doi: 10.1117/1.JBO.18.11.111407
Published in: Journal of Biomedical Optics Volume 18, Issue 11
Show Author Affiliations
Irina Yu. Yanina, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
Natalia A. Trunina, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
Valery V. Tuchin, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)

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