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Journal of Biomedical Optics

Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display
Author(s): Jiawen Li; Teng Ma; Joseph C. Jing; Jun Zhang; Pranav M. Patel; Koping Kirk Shung; Qifa Zhou; Zhongping Chen
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Paper Abstract

We have developed a novel miniature integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5-mm-long rigid part and 0.9-mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding of interventional procedures. By placing the OCT ball lens and IVUS transducer back-to-back at the same axial position, this probe can provide automatically coregistered, coaxial OCT-IVUS imaging. To demonstrate its real-time capability, three-dimensional OCT-IVUS imaging of a pig’s coronary artery displaying in polar coordinates, as well as images of three major types of atherosclerotic plaques in human cadaver coronary segments, were obtained using this probe and our upgraded system. Histology validation is also presented.

Paper Details

Date Published: 21 October 2013
PDF: 4 pages
J. Biomed. Opt. 18(10) 100502 doi: 10.1117/1.JBO.18.10.100502
Published in: Journal of Biomedical Optics Volume 18, Issue 10
Show Author Affiliations
Jiawen Li, Univ. of California, Irvine (United States)
Teng Ma, The Univ. of Southern California (United States)
Joseph C. Jing, Univ. of California, Irvine (United States)
Jun Zhang, Beckman Laser Institute and Medical Clinic (United States)
Pranav M. Patel, Univ. of California, Irvine School of Medicine (United States)
Koping Kirk Shung, The Univ. of Southern California (United States)
Qifa Zhou, The Univ. of Southern California (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)


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