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Journal of Biomedical Optics

Reduction of trial-to-trial variability in functional near-infrared spectroscopy signals by accounting for resting-state functional connectivity
Author(s): Xiao-Su Hu; Keum-Shik Hong; Shuzhi Sam Ge
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Paper Abstract

The reduction of trial-to-trial variability (TTV) in task-evoked functional near-infrared spectroscopy signals by considering the correlated low-frequency spontaneous fluctuations that account for the resting-state functional connectivity in the brain is investigated. A resting-state session followed by a task-state session of a right hand finger-tapping task has been performed on five subjects. Significant ipsilateral and bilateral resting-state functional connectivity has been detected at the subjects’ motor cortex using the seed correlation method. The correlation coefficients obtained during the resting-state are used to reduce the TTV in the signals measured during the task sessions. The results suggest that correlated spontaneous low-frequency fluctuations contribute significantly to the TTV in the task evoked fNIRS signals.

Paper Details

Date Published: 4 January 2013
PDF: 10 pages
J. Biomed. Opt. 18(1) 017003 doi: 10.1117/1.JBO.18.1.017003
Published in: Journal of Biomedical Optics Volume 18, Issue 1
Show Author Affiliations
Xiao-Su Hu, Pusan National Univ. (Korea, Republic of)
Keum-Shik Hong, Pusan National Univ. (Korea, Republic of)
Shuzhi Sam Ge, Pusan National Univ. (Korea, Republic of)

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