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Journal of Biomedical Optics • Open Access

Objective-free optical-resolution photoacoustic microscopy
Author(s): Chulhong Kim; Sung-Jo Park; Jongki Kim; Sungrae Lee; Changho Lee; Mansik Jeon; Jeehyun Kim; Kyunghwan K. Oh

Paper Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) becomes a premier microscopic imaging tool in biomedicine because it provides agent-free optical absorption information in tissues. By tightly focusing light to a spot, a significantly improved lateral resolution can be achieved in OR-PAM. The focal spot size is typically determined by the numerical aperture of the used objective lens. Here, we demonstrate objective-free OR-PAM using a fiber optic Bessel beam generator. In this approach, no objective lens is required and, beneficially, the complexities of conventional OR-PAM systems can be greatly relieved. We have obtained photoacoustic images of a carbon fiber with a diameter of ~ 6 μm, whose lateral resolution was measured to be better than 6 to 7 μm.

Paper Details

Date Published: 11 December 2012
PDF: 3 pages
J. Biomed. Opt. 18(1) 010501 doi: 10.1117/1.JBO.18.1.010501
Published in: Journal of Biomedical Optics Volume 18, Issue 1
Show Author Affiliations
Chulhong Kim, Univ. at Buffalo (United States)
Sung-Jo Park, Kyungpook National Univ. (Korea, Republic of)
Jongki Kim, Yonsei Univ. (Korea, Republic of)
Sungrae Lee, Yonsei Univ. (Korea, Republic of)
Changho Lee, Kyungpook National Univ. (Korea, Republic of)
Mansik Jeon, Univ. at Buffalo (United States)
Jeehyun Kim, Kyungpook National Univ. (Korea, Republic of)
Kyunghwan K. Oh, Yonsei Univ. (Korea, Republic of)

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