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Journal of Biomedical Optics • Open Access

Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms
Author(s): Hamed Azarnoush; Sébastien Vergnole; Valérie Pazos; Charles-Étienne Bisaillon; Benoit Boulet; Guy Lamouche

Paper Abstract

We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was performed to extract the inner and outer diameters of the phantoms at various pressures. The goal for the second scenario was twofold. First, we investigated the IVOCT capability to monitor a more complex balloon inflation process. The balloon was in a folded state prior to inflation. This allowed studying two stages of deformation: during balloon unfolding and during balloon expansion. Second, we investigated IVOCT capability to monitor the deformation in a three-layer phantom used to better mimic a true artery. So, not only were the IVOCT images processed to provide the inner and outer diameters of the phantom, but the layer thicknesses were also determined. In both scenarios, IVOCT monitoring revealed to be very efficient in providing relevant information about the phantom deformation during balloon inflation.

Paper Details

Date Published: 18 September 2012
PDF: 7 pages
J. Biomed. Opt. 17(9) 096015 doi: 10.1117/1.JBO.17.9.096015
Published in: Journal of Biomedical Optics Volume 17, Issue 9
Show Author Affiliations
Hamed Azarnoush, Institut des Matériaux Industriels (Canada)
McGill Univ. (Canada)
Montreal Neurological Hospital and Institute (Canada)
Sébastien Vergnole, Institut des Matériaux Industriels (Canada)
HORIBA Scientific (France)
Valérie Pazos, Institut des Matériaux Industriels (Canada)
Charles-Étienne Bisaillon, Institut des Matériaux Industriels (Canada)
Benoit Boulet, McGill Univ. (Canada)
Guy Lamouche, Institut des Matériaux Industriels (Canada)

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