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Journal of Biomedical Optics • Open Access

Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries
Author(s): Jin U. Kang; Yong Huang; Jaepyeong Cha; Kang Zhang; Zuhaib Ibrahim; W. P. Andrew Lee; Gerald Brandacher; Peter Gehlbach

Paper Abstract

The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10  volume/?startsend? for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8  mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter ∼ 0.1  mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment.

Paper Details

Date Published: 15 May 2012
PDF: 7 pages
J. Biomed. Opt. 17(8) 081403 doi: 10.1117/1.JBO.17.8.081403
Published in: Journal of Biomedical Optics Volume 17, Issue 8
Show Author Affiliations
Jin U. Kang, Johns Hopkins Univ. (United States)
Yong Huang, Johns Hopkins Univ. (United States)
Jaepyeong Cha, Johns Hopkins Univ. (United States)
Kang Zhang, GE Global Research (United States)
Zuhaib Ibrahim, Johns Hopkins Univ. (United States)
W. P. Andrew Lee, Johns Hopkins Univ. (United States)
Gerald Brandacher, Johns Hopkins Univ. (United States)
Peter Gehlbach, Johns Hopkins Univ. (United States)


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