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Journal of Biomedical Optics

Localized thermal mapping using coherent anti-Stokes Raman spectroscopy
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Paper Abstract

Coherent anti-Stokes Raman scattering (CARS) spectroscopy is explored as a tool for obtaining micro-scale thermal measurements. A single femtosecond oscillator is used to pump a photonic crystal fiber to provide the broadband Stokes pulse. The CARS signals from the broad OH-stretching modes between 3000 and 3600 cm-1 are shown to correlate with temperature with an accuracy of ±1°C for water and ±1.5°C for phosphate-buffered saline. Local variation of temperature is mapped on a microscopic level, using black-dyed microspheres as thermal sources.

Paper Details

Date Published: 10 July 2012
PDF: 4 pages
J. Biomed. Opt. 17(8) 080501 doi: 10.1117/1.JBO.17.8.080501
Published in: Journal of Biomedical Optics Volume 17, Issue 8
Show Author Affiliations
Hope T. Beier, Air Force Research Lab. (United States)
Benjamin A. Rockwell, Air Force Research Lab. (United States)
Gary D. Noojin, TASC, Inc. (United States)


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