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Journal of Biomedical Optics

Endoscopic optical coherence tomography device for forward imaging with broad field of view
Author(s): Anke Burkhardt; Julia Walther; Peter Cimalla; Mirko Mehner; Edmund Koch
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Paper Abstract

One current challenge of studying human tympanic membranes (TM) with optical coherence tomography (OCT) is the implementation of optics that avoid direct contact with the inflamed tissue. At the moment, no commercial device is available. We report an optics design for contactless forward imaging endoscopic optical coherence tomography (EOCT) with a large working distance (WD) and a broad field of view (FOV) by restricting the overall diameter of the probe to be small (3.5 mm), ensuring a sufficient numerical aperture. Our system uses a gradient-index (GRIN) relay lens and a GRIN objective lens, and executes a fan-shaped optical scanning pattern. The WD and FOV can be adjusted by manually changing the distance between the triplet and the GRIN relay lens. The measured lateral resolution is ∼28  μm at a WD of 10 mm with a FOV of 10 mm. Additionally, a camera and an illumination beam path were implemented within the probe for image guidance during investigations of the TM. We demonstrated the performance of the EOCT design by 3-D imaging of a human TM ex vivo and in vivo with a k-linear spectral domain OCT system.

Paper Details

Date Published: 16 May 2012
PDF: 6 pages
J. Biomed. Opt. 17(7) 071302 doi: 10.1117/1.JBO.17.7.071302
Published in: Journal of Biomedical Optics Volume 17, Issue 7
Show Author Affiliations
Anke Burkhardt, Univ. Carl Gustav Carus Dresden (Germany)
Julia Walther, Univ. Carl Gustav Carus Dresden (Germany)
Peter Cimalla, Univ. Carl Gustav Carus Dresden (Germany)
Mirko Mehner, Univ. Carl Gustav Carus Dresden (Germany)
Edmund Koch, Univ. Carl Gustav Carus Dresden (Germany)

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