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Journal of Biomedical Optics

Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma
Author(s): Chung-Ku Rhee; Chan Woong Bahk; Se Hyung Kim; Jin-Chul Ahn; Jae-Yun Jung; Phil-Sang Chung; Myung-Whan Suh
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Paper Abstract

We investigated the effect of low-level laser radiation on rescuing hair cells of the cochlea after acute acoustic trauma and hearing loss. Nine rats were exposed to noise. Starting the following day, the left ears (NL ears) of the rats were irradiated at an energy output of 100 to 165  mW  /  cm2 for 60 min for 12 days in a row. The right ears (N ears) were considered as the control group. Frequency-specific hearing levels were measured before the noise exposure and also after the 1st, 3rd to 5th, 8th to 10th and 12th irradiations. After the 12th treatment, hair cells were observed using a scanning electron microscope. Compared to initial hearing levels at all frequencies, thresholds increased markedly after noise exposure. After the 12th irradiation, hearing threshold was significantly lower for the NL ears compared to the N ears. When observed using an electron microscope, the number of hair cells in the middle turn of the NL ears was significantly larger than that of the N ears. Our findings suggest that low-level laser irradiation promotes recovery of hearing thresholds after acute acoustic trauma.

Paper Details

Date Published: 5 June 2012
PDF: 6 pages
J. Biomed. Opt. 17(6) 068002 doi: 10.1117/1.JBO.17.6.068002
Published in: Journal of Biomedical Optics Volume 17, Issue 6
Show Author Affiliations
Chung-Ku Rhee, Dankook Univ. Hospital (Korea, Republic of)
Chan Woong Bahk, Dankook Univ. Hospital (Korea, Republic of)
Univ. of Illinois (United States)
Se Hyung Kim, Jeju National Univ (Republic of Korea)
Jin-Chul Ahn, Dankook Univ. (Republic of Korea)
Jae-Yun Jung, Dankook Univ. (Republic of Korea)
Phil-Sang Chung, Dankook Univ. Hospital (Republic of Korea)
Dankook Univ. (Republic of Korea)
Myung-Whan Suh, Dankook Univ. Hospital (Republic of Korea)

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