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Journal of Biomedical Optics • Open Access

In vivo testing of a prototype system providing simultaneous white light and near infrared autofluorescence image acquisition for detection of bladder cancer
Author(s): Michael C. Jacobson; Ralph W. deVere White; Stavros G. Demos

Paper Abstract

A prototype instrument developed to provide simultaneously ordinary visual endoscopy together with near infrared (NIR) autofluorescence imaging via parallel image acquisition is demonstrated. The two images are recorded concurrently and the instrument interfaces with any ordinary endoscope. Preliminary results of a pilot study focused on imaging of bladder tumors in vivo using this instrumentation are presented. The experimental results demonstrate the capabilities of this instrumentation design, imaging methodology, and define the current limitation for further development of the system.

Paper Details

Date Published: 3 April 2012
PDF: 7 pages
J. Biomed. Opt. 17(3) 036011 doi: 10.1117/1.JBO.17.3.036011
Published in: Journal of Biomedical Optics Volume 17, Issue 3
Show Author Affiliations
Michael C. Jacobson, UC Davis Medical Ctr. (United States)
Ralph W. deVere White, UC Davis Cancer Ctr. (United States)
Stavros G. Demos, Lawrence Livermore National Lab. (United States)


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