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Journal of Biomedical Optics • Open Access

Qualitative investigation of fresh human scalp hair with full-field optical coherence tomography
Author(s): Woo June Choi; Gihyeon Min; Byeong Ha Lee; Long-Quan Pi; Won-Soo Lee

Paper Abstract

We have investigated depth-resolved cellular structures of unmodified fresh human scalp hairs with ultrahigh-resolution full-field optical coherence tomography (FF-OCT). The Linnik-type white light interference microscope has been home-implemented to observe the micro-internal layers of human hairs in their natural environment. In hair shafts, FF-OCT has qualitatively revealed the cellular hair compartments of cuticle and cortex layers involved in keratin filaments and melanin granules. No significant difference between black and white hair shafts was observed except for absence of only the melanin granules in the white hair, reflecting that the density of the melanin granules directly affects the hair color. Anatomical description of plucked hair bulbs was also obtained with the FF-OCT in three-dimensions. We expect this approach will be useful for evaluating cellular alteration of natural hairs on cosmetic assessment or diagnosis of hair diseases.

Paper Details

Date Published: 4 April 2012
PDF: 7 pages
J. Biomed. Opt. 17(3) 036010 doi: 10.1117/1.JBO.17.3.036010
Published in: Journal of Biomedical Optics Volume 17, Issue 3
Show Author Affiliations
Woo June Choi, Gwangju Institute of Science and Technology (Korea, Republic of)
Gihyeon Min, Gwangju Institute of Science and Technology (Korea, Republic of)
Byeong Ha Lee, Gwangju Institute of Science and Technology (Korea, Republic of)
Long-Quan Pi, Wonju College of Medicine (Korea, Republic of)
Won-Soo Lee, Wonju College of Medicine (Korea, Republic of)


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