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Journal of Biomedical Optics • Open Access

Optimization of the open-loop liquid crystal adaptive optics retinal imaging system
Author(s): Ningning Kong; Yue Qi; Li Xuan; Mingliang Xia; Dayu Li; Chao Li

Paper Abstract

An open-loop adaptive optics (AO) system for retinal imaging was constructed using a liquid crystal spatial light modulator (LC-SLM) as the wavefront compensator. Due to the dispersion of the LC-SLM, there was only one illumination source for both aberration detection and retinal imaging in this system. To increase the field of view (FOV) for retinal imaging, a modified mechanical shutter was integrated into the illumination channel to control the size of the illumination spot on the fundus. The AO loop was operated in a pulsing mode, and the fundus was illuminated twice by two laser impulses in a single AO correction loop. As a result, the FOV for retinal imaging was increased to 1.7-deg without compromising the aberration detection accuracy. The correction precision of the open-loop AO system was evaluated in a closed-loop configuration; the residual error is approximately 0.0909λ (root-mean-square, RMS), and the Strehl ratio ranges to 0.7217. Two subjects with differing rates of myopia (-3D and -5D) were tested. High-resolution images of capillaries and photoreceptors were obtained.

Paper Details

Date Published: 22 March 2012
PDF: 7 pages
J. Biomed. Opt. 17(2) 026001 doi: 10.1117/1.JBO.17.2.026001
Published in: Journal of Biomedical Optics Volume 17, Issue 2
Show Author Affiliations
Ningning Kong, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Yue Qi, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Li Xuan, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Mingliang Xia, Suzhou Institute of Biomedical Engineering and Technology (China)
Dayu Li, Suzhou Institute of Biomedical Engineering and Technology (China)
Chao Li, Academy of Military Medical Sciences (China)


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