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Journal of Biomedical Optics

On the sensitivity of thermophotonic lock-in imaging and polarized Raman spectroscopy to early dental caries diagnosis
Author(s): Nima Tabatabaei; Andreas Mandelis; Mehdi Dehghany; Kirk H. Michaelian; Bennett T. Amaechi
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Paper Abstract

Dental caries is the leading cause of tooth loss, which can promptly be prevented if detected in early stages of progression. Unfortunately, conventional diagnostic modalities currently used in dentistry lack the sensitivity to detect early caries. The authors' intention is to compare the ability of polarized Raman spectroscopy and thermophotonic imaging to make early caries diagnosis. Extracted human teeth with no visible stain or defects were artificially demineralized in accordance to a well-known protocol in dentistry for simulated early caries development at several demineralization stages. Samples were then inspected using polarized Raman spectroscopy and thermophotonic imaging. The sensitivities of these two diagnostic modalities are compared, and the results are verified using transverse micro-radiography. It was found that compared to polarized Raman spectroscopy, thermophotonic imaging exhibits superior sensitivity to very early stages of demineralization.

Paper Details

Date Published: 23 February 2012
PDF: 5 pages
J. Biomed. Opt. 17(2) 025002 doi: 10.1117/1.JBO.17.2.025002
Published in: Journal of Biomedical Optics Volume 17, Issue 2
Show Author Affiliations
Nima Tabatabaei, Univ. of Toronto (Canada)
Andreas Mandelis, Univ. of Toronto (Canada)
Mehdi Dehghany, Natural Resources Canada (Canada)
Kirk H. Michaelian, Natural Resources Canada (Canada)
Bennett T. Amaechi, The Univ. of Texas Health Science Ctr. at San Antonio (United States)

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