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Journal of Biomedical Optics

Multifunctional nanoprobe to enhance the utility of optical based imaging techniques
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Paper Abstract

Several imaging modalities such as optical coherence tomography, photothermal, photoacoustic and magnetic resonance imaging, are sensitive to different physical properties (i.e. scattering, absorption and magnetic) that can provide contrast within biological tissues. Usually exogenous agents are designed with specific properties to provide contrast for these imaging methods. In nano-biotechnology there is a need to combine several of these properties into a single contrast agent. This multifunctional contrast agent can then be used by various imaging techniques simultaneously or can be used to develop new imaging modalities. We reported and characterized a multifunctional nanoparticle, made from gold nanoshells, which exhibits scattering, photothermal, photoacoustic, and magnetic properties.

Paper Details

Date Published: 31 January 2012
PDF: 7 pages
J. Biomed. Opt. 17(1) 016015 doi: 10.1117/1.JBO.17.1.016015
Published in: Journal of Biomedical Optics Volume 17, Issue 1
Show Author Affiliations
Yeongri Jung, Univ. of Washington (United States)
Guangying Guan, Univ. of Washington (United States)
Chen-Wei Wei, Univ. of Washington (United States)
Roberto Reif, Univ. of Washington (United States)
Xiaohu Gao, Univ. of Washington (United States)
Matthew O'Donnell, Univ. of Washington (United States)
Ruikang K. Wang, Univ. of Washington (United States)

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