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Journal of Biomedical Optics • Open Access

Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system

Paper Abstract

Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography (ERG) system. The fast IOSs were observed to develop within ∼ 5  ms from the on-set of the visual stimulus, whereas slow IOSs were measured up to 1 s later. The visually evoked IOSs and ERG traces were recorded simultaneously, and a clear correlation was observed between them. The ability to measure visually evoked fast IOSs non-invasively and in vivo from individual retinal layers could significantly improve the understanding of the complex communication between different retinal cell types in healthy and diseased retinas.

Paper Details

Date Published: 8 February 2012
PDF: 6 pages
J. Biomed. Opt. 17(1) 016011 doi: 10.1117/1.JBO.17.1.016011
Published in: Journal of Biomedical Optics Volume 17, Issue 1
Show Author Affiliations
Alireza Akhlagh Moayed, Univ. of Waterloo (Canada)
Sepideh Hariri, Univ. of Waterloo (Canada)
Kostadinka Bizheva, Univ. of Waterloo (Canada)
Vivian Choh, Univ. of Waterloo (Canada)

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