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Journal of Biomedical Optics

Emerging concepts of laser-activated nanoparticles for tissue bonding
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Paper Abstract

We report recent achievements and future perspectives of minimally invasive bonding of biological tissues triggered by laser light. In particular, we review new advancements in the biomedical exploitation of near-infrared absorbing gold nanoparticles as an original solution for the photothermal closure of surgical incisions. Advanced concepts of laser tissue bonding involving the application of hybrid nanocomposites obtained by inclusion of nanochromophores into biopolymer scaffolds are also introduced. The perspectives of tissue bonding are discussed in the following aspects: (1) tissue bonding with highly-stabilized nanochromophores, (2) enhanced tissue bonding with patterned nanocomposites, (3) real-time monitoring of temperature distributions, (4) tracking of tissue regeneration based on the optical resonances of gold nanoparticles.

Paper Details

Date Published: 19 January 2012
PDF: 10 pages
J. Biomed. Opt. 17(1) 010701 doi: 10.1117/1.JBO.17.1.010701
Published in: Journal of Biomedical Optics Volume 17, Issue 1
Show Author Affiliations
Paolo Matteini, Istituto di Fisica Applicata Nello Carrara (Italy)
Fulvio Ratto, Istituto di Fisica Applicata Nello Carrara (Italy)
Francesca Rossi, Istituto di Fisica Applicata Nello Carrara (Italy)
Roberto Pini, Istituto di Fisica Applicata Nello Carrara (Italy)

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