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Journal of Biomedical Optics

Oxygen saturation measurements of blood in retinal vessels during blood loss
Author(s): Matthew H. Smith; Kurt R. Denninghoff; Lloyd W. Hillman; Russell A. Chipman
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Paper Abstract

We describe a noninvasive technique and instrumentation for measuring the oxygen saturation of blood in retinal arteries and veins. The measurements are made by shining low-power lasers into the eye, and scanning the beams across a retinal blood vessel. The light reflected and scattered back out of the eye is collected and measured. The oxygen saturation of blood within the vessel is determined by analyzing the vessel absorption profiles at two wavelengths. A complete saturation measurement can be made in less than 1 s, allowing real-time measurement during physiologic changes. The sensitivity of this measurement technique to changes in retinal saturation has been demonstrated through a series of pilot studies in anesthetized swine. We present data indicating that retinal venous oxygen saturation decreases during ongoing blood loss, demonstrating a potential application of an eye oximeter to noninvasively monitor blood loss.

Paper Details

Date Published: 1 July 1998
PDF: 8 pages
J. Biomed. Opt. 3(3) doi: 10.1117/1.429856
Published in: Journal of Biomedical Optics Volume 3, Issue 3
Show Author Affiliations
Matthew H. Smith, Univ. of Alabama in Huntsville (United States)
Kurt R. Denninghoff, Univ. of Alabama/Birmingham (United States)
Lloyd W. Hillman, Univ. of Alabama in Huntsville (United States)
Russell A. Chipman, Innotech, Johnson and Johnson Inc. (United States)

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