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Optical Engineering

Fabrication of fiber-optic localized surface plasmon resonance sensor and its application to detect antibody-antigen reaction of interferon-gamma
Author(s): Hyeon-Ho Jeong; Seung-Ki Lee; Jae-Hyoung Park; Norov Erdene; Dae-Hong Jeong
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Paper Abstract

A fiber-optic localized surface plasmon (FO LSPR) sensor was fabricated by gold nanoparticles (Au NPs) immobilized on the end-face of an optical fiber. When Au NPs were formed on the end-face of an optical fiber by chemical reaction, Au NPs aggregation occurred and the Au NPs were immobilized in various forms such as monomers, dimers, trimers, etc. The component ratio of the Au NPs on the end-face of the fabricated FO LSPR sensor was slightly changed whenever the sensors were fabricated in the same condition. Including this phenomenon, the FO LSPR sensor was fabricated with high sensitivity by controlling the density of Au NPs. Also, the fabricated sensors were measured for the resonance intensity for the different optical systems and analyzed for the effect on sensitivity. Finally, for application as a biosensor, the sensor was used for detecting the antibody-antigen reaction of interferon-gamma.

Paper Details

Date Published: 1 December 2011
PDF: 9 pages
Opt. Eng. 50(12) 124405 doi: 10.1117/1.3662418
Published in: Optical Engineering Volume 50, Issue 12
Show Author Affiliations
Hyeon-Ho Jeong, Dankook Univ. (Korea, Republic of)
Seung-Ki Lee, Dankook Univ. (Korea, Republic of)
Jae-Hyoung Park, Dankook Univ. (Korea, Republic of)
Norov Erdene, Seoul National Univ. (Korea, Republic of)
Dae-Hong Jeong, Seoul National Univ. (Korea, Republic of)

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