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Journal of Biomedical Optics • Open Access

Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging
Author(s): Dexi Zhu; Ming Li; Yuhong Wang; Lili Ge; Jia Qu; Meixiao Shen; Hong Jiang; Jianhua Wang; Michael R. Wang

Paper Abstract

Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.

Paper Details

Date Published: 1 December 2011
PDF: 8 pages
J. Biomed. Opt. 16(12) 126006 doi: 10.1117/1.3660314
Published in: Journal of Biomedical Optics Volume 16, Issue 12
Show Author Affiliations
Dexi Zhu, Wenzhou Medical College (China)
Ming Li, Wenzhou Medical College (China)
Yuhong Wang, Wenzhou Medical College (China)
Lili Ge, Wenzhou Medical College (China)
Jia Qu, Wenzhou Medical College (China)
Meixiao Shen, Bascom Palmer Eye Institute (United States)
Hong Jiang, Bascom Palmer Eye Institute (United States)
Jianhua Wang, Bascom Palmer Eye Institute (United States)
Michael R. Wang, Univ. of Miami (United States)

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