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Journal of Biomedical Optics • Open Access

Three-dimensional Monte Carlo model of pulsed-laser treatment of cutaneous vascular lesions

Paper Abstract

We present a three-dimensional Monte Carlo model of optical transport in skin with a novel approach to treatment of side boundaries of the volume of interest. This represents an effective way to overcome the inherent limitations of "escape" and "mirror" boundary conditions and enables high-resolution modeling of skin inclusions with complex geometries and arbitrary irradiation patterns. The optical model correctly reproduces measured values of diffuse reflectance for normal skin. When coupled with a sophisticated model of thermal transport and tissue coagulation kinetics, it also reproduces realistic values of radiant exposure thresholds for epidermal injury and for photocoagulation of port wine stain blood vessels in various skin phototypes, with or without application of cryogen spray cooling.

Paper Details

Date Published: 1 December 2011
PDF: 13 pages
J. Biomed. Opt. 16(12) 128002 doi: 10.1117/1.3659205
Published in: Journal of Biomedical Optics Volume 16, Issue 12
Show Author Affiliations
Matija Milanic, Jožef Stefan Institute (Slovenia)
Boris Majaron, Jožef Stefan Institute (Slovenia)

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