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Journal of Biomedical Optics

Dedicated hardware processor and corresponding system-on-chip design for real-time laser speckle imaging
Author(s): Chao Jiang; Hongyan Zhang; Jia Wang; Yaru Wang; Heng He; Rui Liu; Fangyuan Zhou; Jialiang Deng; Pengcheng Li; Qingming Luo
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Paper Abstract

Laser speckle imaging (LSI) is a noninvasive and full-field optical imaging technique which produces two-dimensional blood flow maps of tissues from the raw laser speckle images captured by a CCD camera without scanning. We present a hardware-friendly algorithm for the real-time processing of laser speckle imaging. The algorithm is developed and optimized specifically for LSI processing in the field programmable gate array (FPGA). Based on this algorithm, we designed a dedicated hardware processor for real-time LSI in FPGA. The pipeline processing scheme and parallel computing architecture are introduced into the design of this LSI hardware processor. When the LSI hardware processor is implemented in the FPGA running at the maximum frequency of 130 MHz, up to 85 raw images with the resolution of 640×480 pixels can be processed per second. Meanwhile, we also present a system on chip (SOC) solution for LSI processing by integrating the CCD controller, memory controller, LSI hardware processor, and LCD display controller into a single FPGA chip. This SOC solution also can be used to produce an application specific integrated circuit for LSI processing.

Paper Details

Date Published: 1 November 2011
PDF: 11 pages
J. Biomed. Opt. 16(11) 116008 doi: 10.1117/1.3651772
Published in: Journal of Biomedical Optics Volume 16, Issue 11
Show Author Affiliations
Chao Jiang, Huazhong Univ. of Science and Technology (China)
Hongyan Zhang, Huazhong Univ. of Science and Technology (China)
Jia Wang, Huazhong Univ. of Science and Technology (China)
Yaru Wang, Huazhong Univ. of Science and Technology (China)
Heng He, Huazhong Univ. of Science and Technology (China)
Rui Liu, Huazhong Univ. of Science and Technology (China)
Fangyuan Zhou, Huazhong Univ. of Science and Technology (China)
Jialiang Deng, Huazhong Univ. of Science and Technology (China)
Pengcheng Li, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)


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