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Journal of Biomedical Optics • Open Access

In vivo two-photon microscopy to 1.6-mm depth in mouse cortex
Author(s): Demirhan Kobat; Nicholas G. Horton; Chris Xu

Paper Abstract

Deep tissue in vivo two-photon fluorescence imaging of cortical vasculature in a mouse brain using 1280-nm excitation is presented. A record imaging depth of 1.6 mm in mouse cortex is achieved in vivo, approximately reaching the fundamental depth limit in scattering tissue.

Paper Details

Date Published: 1 October 2011
PDF: 5 pages
J. Biomed. Opt. 16(10) 106014 doi: 10.1117/1.3646209
Published in: Journal of Biomedical Optics Volume 16, Issue 10
Show Author Affiliations
Demirhan Kobat, Cornell Univ. (United States)
Nicholas G. Horton, Cornell Univ. (United States)
Chris Xu, Cornell Univ. (United States)


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