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Journal of Biomedical Optics • Open Access

Terahertz pulsed imaging in vivo: measurements and processing methods
Author(s): Edward P. Parrott; Stanley M. Y. Sy; Thierry Blu; Vincent P. Wallace; Emma Pickwell-MacPherson

Paper Abstract

This paper presents a number of data processing algorithms developed to improve the accuracy of results derived from datasets acquired by a recently designed terahertz handheld probe. These techniques include a baseline subtraction algorithm and a number of algorithms to extract the sample impulse response: double Gaussian inverse filtering, frequency-wavelet domain deconvolution, and sparse deconvolution. In vivo measurements of human skin are used as examples, and a comparison is made of the terahertz impulse response from a number of different skin positions. The algorithms presented enables both the spectroscopic and time domain properties of samples measured in reflection geometry to be better determined compared to previous calculation methods.

Paper Details

Date Published: 1 October 2011
PDF: 9 pages
J. Biomed. Opt. 16(10) 106010 doi: 10.1117/1.3642002
Published in: Journal of Biomedical Optics Volume 16, Issue 10
Show Author Affiliations
Edward P. Parrott, The Chinese Univ. of Hong Kong (Hong Kong, China)
Stanley M. Y. Sy, The Chinese Univ. of Hong Kong (Hong Kong, China)
Thierry Blu, The Chinese Univ. of Hong Kong (Hong Kong, China)
Vincent P. Wallace, The Univ. of Western Australia (Australia)
Emma Pickwell-MacPherson, Hong Kong Univ. of Science and Technology (Hong Kong, China)

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