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Journal of Biomedical Optics • Open Access

Automatic sound speed selection in photoacoustic image reconstruction using an autofocus approach

Paper Abstract

The reconstruction of images in photoacoustic tomography is reliant on specifying the speed of sound within the propagation medium. However, for in vivo imaging, this value is not normally accurately known. Here, an autofocus approach for automatically selecting the sound speed is proposed. This is based on maximizing the sharpness of the reconstructed image as quantified by a focus function. Several focus functions are investigated, and their performance is discussed. The method is demonstrated using phantom measurements made in a medium with a known sound speed and in vivo measurements of the vasculature in the flank of an adult mouse.

Paper Details

Date Published: 1 September 2011
PDF: 4 pages
J. Biomed. Opt. 16(9) 090501 doi: 10.1117/1.3619139
Published in: Journal of Biomedical Optics Volume 16, Issue 9
Show Author Affiliations
Bradley E. Treeby, The Australian National Univ. (Australia)
Trond K. Varslot, The Australian National Univ. (Australia)
Edward Z. Zhang, Univ. College London (United Kingdom)
Jan G. Laufer, Univ. College London (United Kingdom)
Paul C. Beard, Univ. College London (United Kingdom)

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