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Journal of Biomedical Optics • Open Access

Noninvasive imaging of human skin hemodynamics using a digital red-green-blue camera
Author(s): Izumi Nishidate; Noriyuki Tanaka; Tatsuya Kawase; Takaaki Maeda; Tomonori Yuasa; Yoshihisa Aizu; Tetsuya Yuasa; Kyuichi Niizeki

Paper Abstract

In order to visualize human skin hemodynamics, we investigated a method that is specifically developed for the visualization of concentrations of oxygenated blood, deoxygenated blood, and melanin in skin tissue from digital RGB color images. Images of total blood concentration and oxygen saturation can also be reconstructed from the results of oxygenated and deoxygenated blood. Experiments using tissue-like agar gel phantoms demonstrated the ability of the developed method to quantitatively visualize the transition from an oxygenated blood to a deoxygenated blood in dermis. In vivo imaging of the chromophore concentrations and tissue oxygen saturation in the skin of the human hand are performed for 14 subjects during upper limb occlusion at 50 and 250 mm Hg. The response of the total blood concentration in the skin acquired by this method and forearm volume changes obtained from the conventional strain-gauge plethysmograph were comparable during the upper arm occlusion at pressures of both 50 and 250 mm Hg. The results presented in the present paper indicate the possibility of visualizing the hemodynamics of subsurface skin tissue.

Paper Details

Date Published: 1 August 2011
PDF: 15 pages
J. Biomed. Opt. 16(8) 086012 doi: 10.1117/1.3613929
Published in: Journal of Biomedical Optics Volume 16, Issue 8
Show Author Affiliations
Izumi Nishidate, Tokyo Univ. of Agriculture and Technology (Japan)
Noriyuki Tanaka, Tokyo Univ. of Agriculture and Technology (Japan)
Tatsuya Kawase, Tokyo Univ. of Agriculture and Technology (Japan)
Takaaki Maeda, Kushiro National College of Technology (Japan)
Tomonori Yuasa, Muroran Institute of Technology (Japan)
Yoshihisa Aizu, Muroran Institute of Technology (Japan)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Kyuichi Niizeki, Yamagata Univ. (Japan)

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