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Journal of Biomedical Optics • Open Access

Reflection-mode time-reversed ultrasonically encoded optical focusing into turbid media
Author(s): Puxiang Lai; Xiao Xu; Honglin Liu; Yuta Suzuki; Lihong V. Wang

Paper Abstract

Time-reversed ultrasonically encoded (TRUE) optical focusing was recently proposed to deliver light dynamically to a tight region inside a scattering medium. In this letter, we report the first development of a reflection-mode TRUE optical focusing system. A high numerical aperture light guide is used to transmit the diffusely reflected light from a turbid medium to a phase-conjugate mirror (PCM), which is sensitive only to the ultrasound-tagged light. From the PCM, a phase conjugated wavefront of the tagged light is generated and conveyed by the same light guide back to the turbid medium, subsequently converging to the ultrasonic focal zone. We present experimental results from this system, which has the ability to focus light in a highly scattering medium with a round-trip optical penetration thickness (extinction coefficient multiplied by round-trip depth) as large as 160.

Paper Details

Date Published: 1 August 2011
PDF: 4 pages
J. Biomed. Opt. 16(8) 080505 doi: 10.1117/1.3609001
Published in: Journal of Biomedical Optics Volume 16, Issue 8
Show Author Affiliations
Puxiang Lai, Washington Univ. in St. Louis (United States)
Xiao Xu, Washington Univ. in St. Louis (United States)
Honglin Liu, Washington Univ. in St. Louis (United States)
Yuta Suzuki, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


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