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Journal of Biomedical Optics

Transverse chemical interface detection with coherent anti-Stokes Raman scattering microscopy
Author(s): Sophie Brustlein; David Gachet; Franck Billard; Hervé Rigneault
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Paper Abstract

Transverse "chemical" interfaces are revealed with a conventional two beam narrowband coherent anti-Stokes Raman scattering microscopy setup in a collinear configuration. The exciting "pump" and "Stokes" beams are focused on the sample in two opposite directions. The subtraction of the two generated anti-Stokes signals gives rise to a signal that is directly proportional to the pure Raman spectrum of the resonant medium. This property is used to highlight an interface between glass and N,N-dimethylformamide (DMF) and recover the pure Raman spectrum of DMF around its 1408 cm−1 vibrational band.

Paper Details

Date Published: 1 August 2011
PDF: 7 pages
J. Biomed. Opt. 16(8) 086006 doi: 10.1117/1.3606574
Published in: Journal of Biomedical Optics Volume 16, Issue 8
Show Author Affiliations
Sophie Brustlein, Univ. de Franche-Comté (France)
David Gachet, Institut Fresnel (France)
Franck Billard, Institut Fresnel (France)
Hervé Rigneault, Institut Fresnel (France)


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