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Journal of Biomedical Optics • Open Access

Retinal nerve fiber layer retardation measurements using a polarization-sensitive fundus camera
Author(s): Yasufumi Fukuma; Yoshio Okazaki; Takashi Shioiri; Yukio Iida; Hisao Kikuta; Motohiro Shirakashi; Kiyoshi Yaoeda; Haruki Abe; Kazuhiko Ohnuma

Paper Abstract

To measure the retardation distribution of the optic retinal nerve fiber layer (RNFL) from a single image, we have developed a new polarization analysis system that is able to detect the Stokes vector using a fundus camera. The polarization analysis system is constructed with a CCD area image sensor, a linear polarizing plate, a microphase plate array, and a circularly polarized light illumination unit. In this system, the Stokes vector expressing the whole state of polarization is detected, and the influence of the background scattering in the retina and of the retardation caused by the cornea are numerically eliminated. The measurement method is based on the hypothesis that the retardation process of the eye optics can be quantified by a numerical equation that consists of a retardation matrix of all the polarization components. We show the method and the measurement results for normal eyes. Our results indicate that the present method may provide a useful means for the evaluation of retardation distribution of the RNFL.

Paper Details

Date Published: 1 July 2011
PDF: 7 pages
J. Biomed. Opt. 16(7) 076017 doi: 10.1117/1.3600772
Published in: Journal of Biomedical Optics Volume 16, Issue 7
Show Author Affiliations
Yasufumi Fukuma, Topcon Corp. (Japan)
Yoshio Okazaki, Topcon Corp. (Japan)
Takashi Shioiri, Topcon Corp. (Japan)
Yukio Iida, Komazawa Univ. (Japan)
Hisao Kikuta, Osaka Prefecture Univ. (Japan)
Motohiro Shirakashi, Niigata Univ. (Japan)
Kiyoshi Yaoeda, Niigata Univ. (Japan)
Haruki Abe, Niigata Univ. (Japan)
Kazuhiko Ohnuma, Chiba Univ. (Japan)


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