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Journal of Biomedical Optics • Open Access

In vivo determination of acute myocardial ischemia based on photoacoustic imaging with a focused transducer
Author(s): Zhifang Li; Hui Li; Wengming Xie; Haiyu Chen

Paper Abstract

The location and ischemia extent are two important parameters for evaluating the acute myocardial ischemia (AMI). A focused-transducer-based photoacoustic imaging method was employed to assess time-dependent AMI. Our preliminary results show that the photoacoustic signal could identify the myocardium. The intensity and area of photoacoustic images of myocardium could be used for characterizing the ischemia extent and scope of myocardial ischemia. The results also imply that the intensity and area of photoacoustic images are the rapid fall of an exponential model with an increase of delaying time after the left anterior descending coronary artery (LAD) occlusion. These experimental results were consistent with the clinical characteristics. The findings suggest that the photoacoustic imaging be a potential tool for the real-time assessment of acute myocardial ischemia during surgical operation.

Paper Details

Date Published: 1 July 2011
PDF: 7 pages
J. Biomed. Opt. 16(7) 076011 doi: 10.1117/1.3598314
Published in: Journal of Biomedical Optics Volume 16, Issue 7
Show Author Affiliations
Zhifang Li, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Wengming Xie, Fujian Normal Univ. (China)
Haiyu Chen, Fujian Medical Univ. (China)

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