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Journal of Biomedical Optics • Open Access

Remote positioning optical breast magnetic resonance coil for slice-selection during image-guided near-infrared spectroscopy of breast cancer
Author(s): Michael A. Mastanduno; Shudong Jiang; Brian W. Pogue; Keith D. Paulsen; Roberta M. DiFlorio-Alexander

Paper Abstract

The design and testing of a pneumatic optical positioning interface produced with the goal of improving fiber positioning in magnetic resonance (MR)-guided diffuse spectral imaging of breast cancer is presented. The system was created for vertical positioning of optical fibers inside the MR bore during a patient exam to target suspicious lesions with MR scans for reference and collect multiple planes of optical data. The interface includes new fiber plates for mechanical and optical coupling to the breast, and was tested in phantoms and human imaging. Reconstructions with data taken in the new interface show acceptable linearity over different absorber concentrations (residual norm = 0.067), and exhibit good contrast recovery at different imaging planes, which is consistent with previous work. An example of human breast imaging through the new interface is shown and a discussion of how it compares to other patient interfaces for breast imaging is presented. Design goals of increasing the available degrees of freedom for fiber positioning while maintaining good patient-fiber contact and comfort were accomplished. This interface allows improved volumetric imaging with interactive and accurate slice selection to quantify targeted suspicious lesions.

Paper Details

Date Published: 1 June 2011
PDF: 9 pages
J. Biomed. Opt. 16(6) 066001 doi: 10.1117/1.3587631
Published in: Journal of Biomedical Optics Volume 16, Issue 6
Show Author Affiliations
Michael A. Mastanduno, Dartmouth College (United States)
Shudong Jiang, Dartmouth College (United States)
Brian W. Pogue, Dartmouth College (United States)
Keith D. Paulsen, Dartmouth College (United States)
Roberta M. DiFlorio-Alexander, Dartmouth Hitchcock Medical Ctr. (United States)

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