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Journal of Biomedical Optics

Towards noncontact skin melanoma selection by multispectral imaging analysis
Author(s): Ilona Kuzmina; Ilze Diebele; Dainis Jakovels; Janis Spigulis; Lauma Valeine; Janis Kapostinsh; Anna Berzina
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Paper Abstract

A clinical trial comprising 334 pigmented and vascular lesions has been performed in three Riga clinics by means of multispectral imaging analysis. The imaging system Nuance 2.4 (CRi) and self-developed software for mapping of the main skin chromophores were used. Specific features were observed and analyzed for malignant skin melanomas: notably higher absorbance (especially as the difference of optical density relative to the healthy skin), uneven chromophore distribution over the lesion area, and the possibility to select the "melanoma areas" in the correlation graphs of chromophores. The obtained results indicate clinical potential of this technology for noncontact selection of melanoma from other pigmented and vascular skin lesions.

Paper Details

Date Published: 1 June 2011
PDF: 4 pages
J. Biomed. Opt. 16(6) 060502 doi: 10.1117/1.3584846
Published in: Journal of Biomedical Optics Volume 16, Issue 6
Show Author Affiliations
Ilona Kuzmina, Univ. of Latvia (Latvia)
Ilze Diebele, Univ. of Latvia (Latvia)
Dainis Jakovels, Univ. of Latvia (Latvia)
Janis Spigulis, Univ. of Latvia (Latvia)
Lauma Valeine, Beauty Clinic 4th Dimension (Latvia)
Janis Kapostinsh, SIA Riga Eastern Clinical Univ. Hospital (Latvia)
Anna Berzina, The Clinic of Laser Plastics (Latvia)

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