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Journal of Biomedical Optics

Extended scan depth optical coherence tomography for evaluating ocular surface shape
Author(s): Meixiao Shen; Lele Cui; Ming Li; Dexi Zhu; Jianhua Wang; Michael R. Wang
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Paper Abstract

Spectral domain optical coherence tomography (SD-OCT) with extended scan depth makes it possible for quantitative measurement of the entire ocular surface shape. We proposed a novel method for ocular surface shape measurement using a custom-built anterior segment SD-OCT, which will serve on the contact lens fitting. A crosshair alignment system was applied to reduce the misalignment and tilting of the eye. An algorithm was developed to automatically segment the ocular surface. We also described the correction of the image distortion from the segmented dataset induced by the nontelecentric scanning system and tested the accuracy and repeatability. The results showed high accuracy of SD-OCT in measuring a bicurved test surface with a maximum height error of 17.4 μm. The repeatability of in vivo measurement was also good. The standard deviations of the height measurement within a 14-mm wide range were all less than 35 μm. This work demonstrates the feasibility of using extended depth SD-OCT to perform noninvasive evaluation of the ocular surface shape.

Paper Details

Date Published: 1 May 2011
PDF: 11 pages
J. Biomed. Opt. 16(5) 056007 doi: 10.1117/1.3578461
Published in: Journal of Biomedical Optics Volume 16, Issue 5
Show Author Affiliations
Meixiao Shen, Bascom Palmer Eye Institute (United States)
Lele Cui, Bascom Palmer Eye Institute (United States)
Ming Li, Bascom Palmer Eye Institute (United States)
Dexi Zhu, Bascom Palmer Eye Institute (United States)
Jianhua Wang, Bascom Palmer Eye Institute (United States)
Michael R. Wang, Univ. of Miami (United States)

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