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Journal of Biomedical Optics • Open Access

Coagulation dynamics of a blood sample by multiple scattering analysis
Author(s): Magalie Faivre; Marie-Line Cosnier; Patrick Pouteau; Philippe Peltié; Anne Planat-Chrétien; Myriam Cubizolles; Christophe Nougier; Claude Negrier

Paper Abstract

We report a new technique to measure coagulation dynamics on whole-blood samples. The method relies on the analysis of the speckle figure resulting from a whole-blood sample mixed with coagulation reagent and introduced in a thin chamber illuminated with a coherent light. A dynamic study of the speckle reveals a typical behavior due to coagulation. We compare our measured coagulation times to a reference method obtained in a medical laboratory.

Paper Details

Date Published: 1 May 2011
PDF: 10 pages
J. Biomed. Opt. 16(5) 057001 doi: 10.1117/1.3573813
Published in: Journal of Biomedical Optics Volume 16, Issue 5
Show Author Affiliations
Magalie Faivre, CEA-LETI (France)
Marie-Line Cosnier, CEA-LETI (France)
Patrick Pouteau, CEA-LETI (France)
Philippe Peltié, CEA-LETI (France)
Anne Planat-Chrétien, CEA-LETI (France)
Myriam Cubizolles, CEA-LETI (France)
Christophe Nougier, Ctr. Hospitalier Univ. de Lyon (France)
Claude Negrier, Ctr. Hospitalier Univ. de Lyon (France)

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