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Journal of Biomedical Optics • Open Access

Contact and contactless diffuse reflectance spectroscopy: potential for recovery monitoring of vascular lesions after intense pulsed light treatment
Author(s): Ilona Kuzmina; Ilze Diebele; Janis Spigulis; Lauma Valeine; Anna Berzina; Anita Abelite

Paper Abstract

Optical fiber contact probe diffuse reflectance spectroscopy and remote multispectral imaging methods in the spectral range of 400 to 1100 nm were used for skin vascular malformation assessment and recovery tracing after treatment by intense pulsed light. The results confirmed that oxy-hemoglobin relative changes and the optical density difference between lesion and healthy skin in the spectral region 500 to 600 nm may be successfully used for objective appraisal of the therapy effect. Color redness parameter a* = 2 is suggested as a diagnostic border to distinguish healthy skin and vascular lesions, and as the indicator of phototreatment efficiency. Valuable diagnostic information on large area (>5 mm) lesions and lesions with uncertain borders can be proved by the multispectral imaging method.

Paper Details

Date Published: 1 April 2011
PDF: 4 pages
J. Biomed. Opt. 16(4) 040505 doi: 10.1117/1.3569119
Published in: Journal of Biomedical Optics Volume 16, Issue 4
Show Author Affiliations
Ilona Kuzmina, Univ. of Latvia (Latvia)
Ilze Diebele, Univ. of Latvia (Latvia)
Janis Spigulis, Univ. of Latvia (Latvia)
Lauma Valeine, Univ. of Latvia (Latvia)
Anna Berzina, The Clinic of Laser Plastics (Latvia)
Anita Abelite, The Clinic of Laser Plastics (Latvia)


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