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Journal of Biomedical Optics • Open Access

Quantitative analysis on collagen morphology in aging skin based on multiphoton microscopy
Author(s): Shulian Wu; Hui Li; Hongqin Yang; Xiaoman Zhang; Zhifang Li; Shufei Xu

Paper Abstract

Multiphoton microscopy was employed for monitoring the structure changes of mouse dermis collagen in the intrinsic- or the extrinsic-age-related processes in vivo. The characteristics of textures in different aging skins were uncovered by fast Fourier transform in which the orientation index and bundle packing of collagen were quantitatively analyzed. Some significant differences in collagen-related changes are found in different aging skins, which can be good indicators for the statuses of aging skins. The results are valuable to the study of aging skin and also of interest to biomedical photonics.

Paper Details

Date Published: 1 April 2011
PDF: 4 pages
J. Biomed. Opt. 16(4) 040502 doi: 10.1117/1.3565439
Published in: Journal of Biomedical Optics Volume 16, Issue 4
Show Author Affiliations
Shulian Wu, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Hongqin Yang, Fujian Normal Univ. (China)
Xiaoman Zhang, Fujian Normal Univ. (China)
Zhifang Li, Fujian Normal Univ. (China)
Shufei Xu, Fujian Normal Univ. (China)


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