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Journal of Biomedical Optics • Open Access

Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters
Author(s): Liming Hu; Biao Wang; Junsheng Cao; Zhenhua Tian; Zhijian Gao; Li Qin; Yun Liu; Lijun Wang; Zhihua Lu; Xiaobo Ma; Xiaodong Wu

Paper Abstract

Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were made on the Wistar rat's dorsal skin. The efficiencies of laser-welding with different parameters were investigated. Incision-healing, histology examination, and a tensile strength test of incisions were recorded. Laser welding with the irradiance level of 15.9 W/cm2 for both 980 and 1064-nm lasers and exposure time of 5 s per spot in continuous wave mode yielded a more effective closure and healing with minimal thermal damage, faster recovery, and stronger apposition in comparison with a suturing technique. The conclusion is that skin welding with a combination of two near-infrared diode lasers can be a good candidate for incision closure, and further investigations are in progress for clinical use.

Paper Details

Date Published: 1 March 2011
PDF: 8 pages
J. Biomed. Opt. 16(3) 038001 doi: 10.1117/1.3552648
Published in: Journal of Biomedical Optics Volume 16, Issue 3
Show Author Affiliations
Liming Hu, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Biao Wang, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Junsheng Cao, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Zhenhua Tian, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Zhijian Gao, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Li Qin, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Yun Liu, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Lijun Wang, Changchun Institute of Optics, Fine Mechanics and Physics (China)
Zhihua Lu, First Hospital of Jilin Univ. (China)
Xiaobo Ma, First Hospital of Jilin Univ. (China)
Xiaodong Wu, Suzhou Institute of Biomedical Engineering and Technology (China)


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