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Journal of Biomedical Optics • Open Access

Speckle reduction in optical coherence tomography images using tissue viscoelasticity
Author(s): Brendan F. Kennedy; Andrea Curatolo; David D. Sampson; Timothy R. Hillman; Christobel Saunders

Paper Abstract

We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution.

Paper Details

Date Published: 1 February 2011
PDF: 3 pages
J. Biomed. Opt. 16(2) 020506 doi: 10.1117/1.3548239
Published in: Journal of Biomedical Optics Volume 16, Issue 2
Show Author Affiliations
Brendan F. Kennedy, The Univ. of Western Australia (Australia)
Andrea Curatolo, The Univ. of Western Australia (Australia)
David D. Sampson, The Univ. of Western Australia (Australia)
Timothy R. Hillman, Massachusetts Institute of Technology (United States)
Christobel Saunders, The Univ. of Western Australia (Australia)


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