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Journal of Biomedical Optics • Open Access

Revealing retroperitoneal liposarcoma morphology using optical coherence tomography
Author(s): Esteban F. Carbajal; Stepan A. Baranov; Venu G. R. Manne; Kirill V. Larin; Eric D. Young; Alexander J. Lazar; Dina C. Lev; Raphael E. Pollock

Paper Abstract

A new approach to distinguish normal fat, well-differentiated (WD), and dedifferentiated liposarcoma (LS) tumors is demonstrated, based on the use of optical coherence tomography (OCT). OCT images show the same structures seen with conventional histological methods. Our visual grading analysis is supported by numerical analysis of observed structures for normal fat and WDLS samples. Further development could apply the real-time and high resolution advantages of OCT for use in liposarcoma diagnosis and clinical procedures.

Paper Details

Date Published: 1 February 2011
PDF: 3 pages
J. Biomed. Opt. 16(2) 020502 doi: 10.1117/1.3541789
Published in: Journal of Biomedical Optics Volume 16, Issue 2
Show Author Affiliations
Esteban F. Carbajal, Univ. of Houston (United States)
Stepan A. Baranov, Univ. of Houston (United States)
Venu G. R. Manne, Univ. of Houston (United States)
Kirill V. Larin, Univ. of Houston (United States)
Eric D. Young, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Alexander J. Lazar, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Dina C. Lev, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Raphael E. Pollock, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)


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