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Journal of Biomedical Optics

Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber
Author(s): Yong Zhou; Nan Zeng; Yanhong Ji; Yao Li; Xiangsong Dai; Peng Li; Lian Duan; Hui Ma; Yonghong He
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Paper Abstract

We present a method of glucose concentration detection in the anterior chamber with a differential absorption optical low-coherent interferometry (LCI) technique. Back-reflected light from the iris, passing through the anterior chamber twice, was selectively obtained with the LCI technique. Two light sources, one centered within (1625 nm) and the other centered outside (1310 nm) of a glucose absorption band were used for differential absorption measurement. In the eye model and pig eye experiments, we obtained a resolution glucose level of 26.8 mg/dL and 69.6 mg/dL, respectively. This method has a potential application for noninvasive detection of glucose concentration in aqueous humor, which is related to the glucose concentration in blood.

Paper Details

Date Published: 1 January 2011
PDF: 7 pages
J. Biomed. Opt. 16(1) 015004 doi: 10.1117/1.3528658
Published in: Journal of Biomedical Optics Volume 16, Issue 1
Show Author Affiliations
Yong Zhou, Tsinghua Univ. (China)
Nan Zeng, Tsinghua Univ. (China)
Yanhong Ji, South China Normal Univ. (China)
Yao Li, Tsinghua Univ. (China)
Xiangsong Dai, Tsinghua Univ. (China)
Peng Li, Tsinghua Univ. (China)
Lian Duan, Tsinghua Univ. (China)
Hui Ma, Tsinghua Univ. (China)
Yonghong He, Tsinghua Univ. (China)

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