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Journal of Biomedical Optics • Open Access

Simultaneous assessment of pulsating and total blood in inflammatory skin lesions using functional diffuse reflectance spectroscopy in the visible range

Paper Abstract

We present a simple and cost-effective optical technique for the simultaneous assessment of pulsating and total blood noninvasively in an inflammatory skin lesion. Acquisitions of diffuse reflectance spectra in the visible range at 6 Hz are used to trace the oscillating components of reflectance. Measurements on erythematous lesions from a UV insult show slow changing signal at about 0.1 Hz and heart-driven regular oscillations at about 1 Hz simultaneously. The results demonstrate the potential of the technique in monitoring both pulsating and steady components of the blood in inflammatory lesions of the skin.

Paper Details

Date Published: 1 November 2010
PDF: 3 pages
J. Biomed. Opt. 15(6) 060507 doi: 10.1117/1.3524191
Published in: Journal of Biomedical Optics Volume 15, Issue 6
Show Author Affiliations
InSeok Seo, Johnson & Johnson CPPW (United States)
Paulo R. Bargo, Johnson & Johnson CPPW (United States)
Nikiforos Kollias, Johnson & Johnson CPPW (United States)

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