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Journal of Biomedical Optics

Endoscopic low-coherence topography measurement for upper airways and hollow samples
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Paper Abstract

To evaluate the severity of airway pathologies, quantitative dimensioning of airways is of utmost importance. Endoscopic vision gives a projective image and thus no true scaling information can be directly deduced from it. In this article, an approach based on an interferometric setup, a low-coherence laser source and a standard rigid endoscope is presented, and applied to hollow samples measurements. More generally, the use of the low-coherence interferometric setup detailed here could be extended to any other endoscopy-related field of interest, e.g., gastroscopy, arthroscopy and other medical or industrial applications where tri-dimensional topology is required. The setup design with a multiple fibers illumination system is presented. Demonstration of the method ability to operate on biological samples is assessed through measurements on ex vivo pig bronchi.

Paper Details

Date Published: 1 November 2010
PDF: 6 pages
J. Biomed. Opt. 15(6) 066014 doi: 10.1117/1.3512218
Published in: Journal of Biomedical Optics Volume 15, Issue 6
Show Author Affiliations
Yves Delacrétaz, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Etienne Shaffer, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Nicolas Pavillon, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Jonas Kuhn, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Florian Lang, Ctr. Hospitalier Univ. Vaudois (Switzerland)
Christian D. Depeursinge, Ecole Polytechnique Fédérale de Lausanne (Switzerland)

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