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Journal of Biomedical Optics • Open Access

Noninvasive observation of skeletal muscle contraction using near-infrared time-resolved reflectance and diffusing-wave spectroscopy
Author(s): Markus Belau; Markus Ninck; Gernot Hering; Lorenzo Spinelli; Davide Contini; Alessandro Torricelli; Thomas Gisler

Paper Abstract

We introduce a method for noninvasively measuring muscle contraction in vivo, based on near-infrared diffusing-wave spectroscopy (DWS). The method exploits the information about time-dependent shear motions within the contracting muscle that are contained in the temporal autocorrelation function g(1) (,t) of the multiply scattered light field measured as a function of lag time, , and time after stimulus, t. The analysis of g(1) (,t) measured on the human M. biceps brachii during repetitive electrical stimulation, using optical properties measured with time-resolved reflectance spectroscopy, shows that the tissue dynamics giving rise to the speckle fluctuations can be described by a combination of diffusion and shearing. The evolution of the tissue Cauchy strain e(t) shows a strong correlation with the force, indicating that a significant part of the shear observed with DWS is due to muscle contraction. The evolution of the DWS decay time shows quantitative differences between the M. biceps brachii and the M. gastrocnemius, suggesting that DWS allows to discriminate contraction of fast- and slow-twitch muscle fibers.

Paper Details

Date Published: 1 September 2010
PDF: 8 pages
J. Biomed. Opt. 15(5) 057007 doi: 10.1117/1.3503398
Published in: Journal of Biomedical Optics Volume 15, Issue 5
Show Author Affiliations
Markus Belau, Univ. Konstanz (Germany)
Markus Ninck, Univ. Konstanz (Germany)
Gernot Hering, Univ. Konstanz (Germany)
Lorenzo Spinelli, Consiglio Nazionale delle Ricerche (Italy)
Davide Contini, Politecnico di Milano (Italy)
Alessandro Torricelli, Politecnico di Milano (Italy)
Thomas Gisler, Univ. Konstanz (Germany)

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