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Journal of Biomedical Optics

Digital holographic microscopy by use of surface plasmon resonance for imaging of cell membranes
Author(s): Cuiying Hu; Jingang Zhong; Jiawen Weng
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Paper Abstract

A technique called surface plasmon resonance digital holographic microscopy (SPRDHM) for optical imaging of cell membranes is proposed. The intensity and phase distributions of the reflected light that is modulated by the cell membrane in surface plasmon resonance can be simultaneously obtained. The imaging principle and capability are theoretically analyzed and demonstrated by experiments. In addition, the technique is compared with total internal reflection digital holographic microscopy (TIRDHM) in theory and experiment, respectively. The results show that the SPRDHM technique is better in spatial resolution and phase sensitivity than the TIRDHM technique for imaging of cell membranes

Paper Details

Date Published: 1 September 2010
PDF: 8 pages
J. Biomed. Opt. 15(5) 056015 doi: 10.1117/1.3497564
Published in: Journal of Biomedical Optics Volume 15, Issue 5
Show Author Affiliations
Cuiying Hu, Jinan Univ. (China)
Jingang Zhong, Jinan Univ. (China)
Jiawen Weng, Jinan Univ. (China)

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