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Journal of Biomedical Optics • Open Access

Comparison of phase-shifting techniques for in vivo full-range, high-speed Fourier-domain optical coherence tomography

Paper Abstract

Single spectrometer-based complex conjugate artifact removal methods are evaluated for in vivo imaging with complementary metal-oxide semiconductor line scan camera based high-speed Fourier-domain optical coherence tomography (FD-OCT) at 100,000 axial scans per second. Performance of three different phase-shifting methods with the same OCT engine is evaluated using modified data acquisition schemes, depending on the requirements of each phase-shifting technique. The suppression ratio of complex conjugate artifact images using a paperboard is assessed for all tested methods. Several other characteristics, including a list of additional hardware requirements (beyond standard FD-OCT components) and data acquisition schemes for each of the methods is presented. In vivo full-range images of human fingerpad and nail are shown and compared with standard FD-OCT images. Additionally, a complex-conjugate-free human retinal volume acquired at the speed of 100,000 A-scans/s is presented.

Paper Details

Date Published: 1 September 2010
PDF: 8 pages
J. Biomed. Opt. 15(5) 056011 doi: 10.1117/1.3494556
Published in: Journal of Biomedical Optics Volume 15, Issue 5
Show Author Affiliations
Dae Yu Kim, UC Davis Medical Ctr. (United States)
John S. Werner, UC Davis Medical Ctr. (United States)
Robert J. Zawadzki, UC Davis Medical Ctr. (United States)

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